何涛，博士，副研究员，主持或参与多项国家及省部级科研项目，致力于生物医用纳米与水凝胶材料的开发，主要从事新型免疫佐剂与靶向药物递送系统在肿瘤免疫治疗中的研究。以第一作者（含共一）在Acta Pharmaceutica Sinica B、Biomaterials、Acta Biomaterialia、Theranostics、Advanced Healthcare Materials等国际杂志发表SCI论文多篇。
科研项目：
1. 四川省自然科学基金青年项目 “调控细胞焦亡的智能响应纳米药物系统级联增效新辅助化疗-免疫治疗协同抗乳腺癌术后复发与转移的研究”（2023NSFSC1594）2023.01-2024.12，主持。
2. 四川大学专职博士后研发基金“表观遗传调控细胞焦亡的肿瘤免疫循环增强型纳米系统构建及其在乳腺癌新辅助免疫治疗中的作用和机制研究”（2023SCU12068）2023.01-2024.12，主持。
3. 四川大学博士后交叉学科创新启动基金项目“级联STING激活的原位抗原捕获新辅助纳米系统构建及其在结直肠癌术前干预并预防术后转移和复发的研究” 2023.01-2024.12，主持。
代表性科研成果：
1. Tao He, Mingxing Hu, Shunyao Zhu, Meiling Shen, Xiaorong Kou, Xiuqi Liang, Lu Li, Xinchao Li, Miaomiao Zhang, Qinjie Wu*,Changyang Gong*. A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence, Acta Pharmaceutica Sinica B, 2023, 13(2): 804-818 （中科院一区，IF=14.7）
2. Tao He#, Yiling Shi#, Xiaorong Kou, Meiling Shen, Xiuqi Liang, Xinchao Li, Rui Wu,Yanjie You, Qinjie Wu, Changyang Gong*. Antigenicity and adjuvanticity co-reinforced personalized cell vaccines based on self-adjuvanted hydrogel for post-surgical cancer vaccination, Biomaterials, 2023, 301, 122218. (#Contributed equally).（中科院一区，IF=12.8）
3. Tao He, Xiuqi Liang, Lu Li, Songlin Gong, Xinchao Li, Miaomiao Zhang, Shunyao Zhu, Haitao Xiao, Qinjie Wu*, Changyang Gong*. A spontaneously formed and self-adjuvanted hydrogel vaccine triggers strong immune responses, Materials & Design, 2021, 197(109232). （中科院二区，IF=7.6）
4. Tao He, Chang Zou, Linjiang Song, Ning Wang, Suleixin Yang, Yan Zeng, Qinjie Wu, Wenli Zhang, Yingtai Chen*, and Changyang Gong*. Improving antiadhesion effect of thermosensitive hydrogel with sustained release of tissue-type plasminogen activator in a rat repeated-injury model, ACS Applied Materials & Interface, 2016, 8(49): 33514-33520. （中科院二区，IF=8.3）
5. Shunyao Zhu#, Tao He#, Yan Wang, Yushan Ma, Wenmei Li, Songlin Gong, Yanghui Zhu, Xiangwei Wang, Xu Xu, Qinjie Wu, Changyang Gong*, Yanjie You*. A hierarchically acidity-unlocking nanoSTING stimulant enables cascaded STING activation for potent innate and adaptive antitumor immunity, Theranostics, 2024, 14(15): 5984-5998. (#Contributed equally). （中科院一区，IF=12.4）
6. Xiaorong Kou#, Tao He#, Miaomiao Zhang, Xinyue Wu, Xinchao Li, Rui Luo, Rui Wu, Xinyu Gou, Meiling Shen, Qinjie Wu, and Changyang Gong*. A Multivalent Personalized Vaccine Orchestrating Two-Signal Activation Rebuilds the Bridge Between Innate and Adaptive Antitumor Immunity, Small Methods, 2023, 7(10), 2300019. (#Contributed equally). （中科院二区，IF=10.7）
7. Furong Liu#, Tao He#, Songlin Gong, Meiling Shen, Shuang Ma, Xianzhou Huang, Lu Li, Li Wang, Qinjie Wu*, Changyang Gong*. A tumor pH-responsive autocatalytic nanoreactor as a H2O2 and O2 self-supplying depot for enhanced ROS-based chemo/photodynamic therapy, Acta Biomaterialia, 2022, 154: 510-522. (#Contributed equally). （中科院一区，IF=9.4）
8. Zichao Luo#; Tao He#; Peng Liu, Zhigao Yi, Shunyao Zhu, Xiuqi Liang, Entang Kang, Changyang Gong*, and Xiaogang Liu*. Self-adjuvanted molecular activator (SeaMac) nanovaccines promote cancer immunotherapy, Advanced Healthcare Materials, 2021, 10(7): 2002080. (#Contributed equally). （中科院二区，IF=10.0）
9. Ning Wang#, Tao He# Yangmei Shen, Linjiang Song, Ling Li, Xi Yang, Xia Li, Mengru Pang, Weijun Su, Xinyu Liu*, Qinjie Wu*, and Changyang Gong*,. Paclitaxel and tacrolimus coencapsulated polymeric micelles that enhance the therapeutic effect of drug-resistant ovarian cancer, ACS Applied Materials & Interface, 2016, 8(49): 33514-33520. (#Contributed equally). （中科院二区，IF=8.3）
热忱欢迎药剂学、制药工程、化学生物学、基础及临床医学等相关专业本科生到课题组实习，共同进步。
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